Microdeletion Syndromes

Vysis Prader-Willi/Angelman Region SNRPN/CEP 15/PML FISH Probe Kit

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Product Description

The Vysis Prader-Willi/Angelman Region SNRPN/CEP 15/PML FISH Probe Kit is intended to detect the large common deletion involving the SNRPN gene region on chromosome region 15q11-q13 using the fluorescence in situ hybridization (FISH) technique.

The approximately 125 kb (chr15:22716001-22841074; March 2006 assembly, UCSC Genome Browser) SpectrumOrange LSI SNRPN probe spans the SNURF-SNRPN locus on chromosome region 15q11-q13. The approximately 239 kb (chr15:71877721-72116436; March 2006 assembly, UCSC Genome Browser) SpectrumGreen LSI PML probe is located at the chromosome region 15q22-q24. The SpectrumAqua CEP 15 (D15Z1) probe is located at chromosome region 15p11.2.

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