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CEP 8 is a SpectrumOrange labeled probe specific for the alpha satellite (centromeric) region, 8p11.1-q11.1.
The CEP 8 DNA Probe Kit which is available for in vitro diagnostic use and may be used as an adjunct to standard karotyping to identify and enumerate chromosome 8 in cells obtained from bone marrow. In multi-site clinical trials, the CEP 8 DNA Probe Kit for interphase analysis was 96% sensitive and 98% specific as compared to traditional cytogenetic analysis. A close association has been made between trisomy 8 and both myeloid blast crisis and basophilia. Trisomy 8 is a prevalent genetic aberration in several specific diseases:
Components of the CEP 8 SpectrumOrange DNA Probe Kit include:
For In Vitro Diagnostic Use
To learn more about Vysis CEP 8 SpectrumOrange Direct Labeled Fluorescent DNA Probe Kit please visit: https://www.molecular.abbott/us/en/products/vysis-cep-8-dna-probe-kit
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