Chronic Myelogenous Leukemia (CML)

Vysis LSI 9q34 SpectrumAqua FISH Probe Kit

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Product Description
RESULTS OF HYBRIDIZATION
Product Description

The Vysis LSI 9q34 SpectrumAqua FISH Probe Kit is intended to detect deletion of the Vysis 9q34 probe target region using the fluorescence in situ hybridization (FISH) technique.

The approximately 329 kb (chr9:132255025-132584487; March 2006 assembly) SpectrumAqua probe spans the ASS1 gene at 9q34.

RESULTS OF HYBRIDIZATION
This probe is provided for those interested in assessing the deletion status of the 9q34 region of chromosome 9. In a normal cell with two intact copies of chromosome 9, two aqua signals will be observed. In an abnormal cell that has lost the 9q34 region of chromosome 9, fewer than two aqua signals will be observed.
Normal Hybridization: Result of the hybridization of the LSI 9q34 Probe as observed in a normal interphase cell.
Abnormal Hybridization: Abnormal cell hybridized with the LSI 9q34 Probe. The cell in this image shows deletion of one copy of the 9q34 region of chromosome 9 as indicated by the single aqua signal

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