Vysis LSI AURKA SpectrumGold FISH Probe Kit

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Product Description
RESULTS OF HYBRIDIZATION
Product Description

The Vysis LSI AURKA SpectrumGold FISH Probe Kit is designed to detect the copy number of Aurora Kinase A (AURKA) locus localized in chromosome 20 at the 20q13.2 band via fluorescence in situ hybridization (FISH) in human urine specimens.

The approximately 650 Kb SpectrumGold AURKA (20q13.2) probe encompasses the entire 23 Kb AURKA gene on chromosome 20 and adjacent regions, extending from a point centromeric of the AURKA gene to a point telomeric of the AURKA gene.

RESULTS OF HYBRIDIZATION
Normal Hybridization: In a nucleus with a normal copy number of the AURKA gene, two gold signals will be observed.
Abnormal Hybridization: Abnormal copy number of the AURKA gene is indicated by more than two copies of the gold probe signal. Disregard nuclei with less than 2 copies of the gold probe signal.

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