Vysis LSI CCND1 (11q13) Dual Color, Break Apart Rearrangement Probe Kit

For more information, contact Abbott.

Contact
Product Name Unit Size Order Number GTIN
Product Description
RESULTS OF HYBRIDIZATION
Product Description

The Vysis CCND1 Dual Color Break Apart Rearrangement FISH probe is intended to detect chromosomal rearrangements involving the Cyclin D1 (CCND1) gene region at chromosome 11q13.

The SpectrumGreen probe is located centromeric to CCND1 and spans approximately 695 kb (chr11:68042961-68737635; March 2006 assembly) with an approximately 30 kb gap (chr11:68539031-68568615; March 2006 assembly). The SpectrumOrange probe spans approximately 532 kb (chr11:69162485-69694376; March 2006 assembly)4 and covers CCND1.

RESULTS OF HYBRIDIZATION

The anticipated signal pattern in abnormal cells having a chromosomal breakpoint within the gap between the two probe targets on one chromosome 11 is one orange, one green, and one fusion signal. Other patterns may be observed if additional genetic alterations are present. Hybridization of this probe to interphase nuclei of normal cells is expected to produce two pair of overlapping, or nearly overlapping, orange and green (yellow fusion) signals.

Normal Hybridization: Normal cell hybridization using the LSI CCND1 (11q13) Dual Color Break Apart Rearrangement Probe.
Abnormal Hybridization: Abnormal cell hybridization using the LSI CCND1 (11q13) Dual Color Break Apart Rearrangement Probe.

You are about to exit the Abbott family of websites for a 3rd party website

Links which take you out of Abbott worldwide websites are not under the control of Abbott, and Abbott is not responsible for the contents of any such site or any further links from such site. Abbott is providing these links to you only as a convenience, and the inclusion of any link does not imply endorsement of the linked site by Abbott. The website that you have requested also may not be optimised for your screen size.

Do you wish to continue and exit this website?

Yes No

You are about to enter an Abbott country or region specific website.

Please be aware that the website you have requested is intended for the residents of a particular country or countries, as noted on that site. As a result, the site may contain information on pharmaceuticals, medical devices and other products or uses of those products that are not approved in other countries or regions.

Do you wish to continue and enter this website?

Yes No

You are about to enter an Abbott country or region specific website.

Please be aware that the website you have requested is intended for the residents of a particular country or countries, as noted on that site. As a result, the site may contain information on pharmaceuticals, medical devices and other products or uses of those products that are not approved in other countries or regions.

Do you wish to continue and enter this website?

Yes No