Vysis LSI IGH/BCL2 Dual Color, Dual Fusion Translocation Probe Set

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Vysis LSI IGH/BCL2 Dual Color, Dual Fusion Translocation Probe Set is intended to detect the t(14;18)(q32;q21) that juxtaposes the IGH (immunoglobulin heavy chain) locus and the BCL2 (B-cell leukemia/lymphoma) gene.

The Vysis LSI IGH/BCL2 Dual Color, Dual Fusion Translocation Probe is a mixture of a SpectrumGreen LSI IGH probe and a SpectrumOrange BCL2 probe. The LSI IGH probe spans about a 1.6 Mb target and contains sequences covering essentially the entire IGH locus, as well as sequences extending about 300 kb beyond the 3′ end of the IGH locus. The LSI BCL2 probe spans approximately 870 kb of sequence, contains the entire BCL2 gene, and extends for about 141kb telomeric of the gene and about 533 kb centromeric of the gene.