Non-Hodgkins Lymphoma

Vysis LSI IGH/MALT1 DF FISH Probe Kit

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Product Description
RESULTS OF HYBRIDIZATION
Product Description

The Vysis IGH/MALT1 DF FISH Probe Kit is intended to detect the t(14;18)(q32;q21) reciprocal translocation involving the IGH and MALT1 gene regions using the fluorescence in situ hybridization (FISH) technique.

The SpectrumOrange probe spans approximately 670 kb (chr18:54220804-54891192; March 2006 assembly) and covers the MALT1 gene region. The approximately 1.6 Mb SpectrumGreen probe spans the IGH region (chr14:104736507-106339460; March 2006 assembly).

RESULTS OF HYBRIDIZATION
Normal Hybridization: Result of the hybridization of the LSI IGH/MALT1 t(14;18)(q32;q21) Dual Color, Dual Fusion Translocation Probe as observed in interphase cells.
Abnormal Hybridization: Cell hybridized with the LSI IGH/MALT1 t(14;18)(q32;q21) Dual Color, Dual Fusion Translocation Probe. The cell in this image shows the one orange, one green and two fusion signal pattern.

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