Vysis LSI MYB SpectrumAqua FISH Probe Kit

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Product Description
RESULTS OF HYBRIDIZATION
Product Description

This fluorescence in situ hybridization (FISH) probe is intended to detect the copy number of the LSI MYB probe target located at chromosome 6q23.

The approximately 743 kb SpectrumAqua LSI MYB (6q23) probe contains the complete MYB gene and is located at chromosome 6q23. (chr6:135117337-135860164; March 2006 assembly, UCSC Genome Browser).

RESULTS OF HYBRIDIZATION
Hybridization of this probe to interphase and metaphase nuclei of normal cells is expected to be seen as two aqua signals. The anticipated signal pattern in individuals with a deletion of the 6q23 region would be seen as a single aqua signal. Other patterns may be observed if additional genetic alterations are present.
Normal Hybridization: Normal cell hybridization using the Vysis LSI MYB (6q23) Probe.
Abnormal Hybridization: Abnormal cell hybridization using the Vysis LSI MYB (6q23) Probe.

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