Molecular Catalog
Molecular Catalog
Acute Lymphocytic Leukemia (ALL)

Vysis LSI TCF3/PBX1 Dual Color, Dual Fusion Translocation Probe

For more information, contact Abbott.

Contact
Large Product Thumbnail
Product Description
Results of Hybridization
Product Description

Vysis LSI TCF3/ PBX1 Dual Color, Dual Fusion Translocation Probe hybridizes to chromosome 19p13.3 (TCF3 - Spectrum Green) and chromosome 1q23 (PBX1 - Spectrum Orange). The PBX1 probe is 635 kb in size and covers the entire PBX1 gene on chromosome 1q23. The TCF3 probe is 730 kb in size and the green probe extends beyond the TCF3 gene to cover a larger region on chromosome 19p13.3. .

The signals may also appear diffuse or split depending upon the condensation of the DNA and the relative distances between chromatids. The hybridized probe fluoresces with moderate to bright intensity both in interphase nuclei and on metaphase chromosomes. In interphase nuclei of normal cells, the probe generally appears as two distinct orange signals and two distinct green signals.

Results of Hybridization
Normal Hybridization: Normal hybridization showing two orange and two green signals.
Abnormal Hybridization: Example abnormal hybridization showing two orange, one green and one fusion signals.
  • Vysis FISH
  • Abbott REAL-TIME PCR
  • Ordering Information
Back

You are about to exit the Abbott family of websites for a 3rd party website

Links which take you out of Abbott worldwide websites are not under the control of Abbott, and Abbott is not responsible for the contents of any such site or any further links from such site. Abbott is providing these links to you only as a convenience, and the inclusion of any link does not imply endorsement of the linked site by Abbott. The website that you have requested also may not be optimised for your screen size.

Do you wish to continue and exit this website?

Yes No

You are about to enter an Abbott country or region specific website.

Please be aware that the website you have requested is intended for the residents of a particular country or countries, as noted on that site. As a result, the site may contain information on pharmaceuticals, medical devices and other products or uses of those products that are not approved in other countries or regions.

Do you wish to continue and enter this website?

Yes No

You are about to enter an Abbott country or region specific website.

Please be aware that the website you have requested is intended for the residents of a particular country or countries, as noted on that site. As a result, the site may contain information on pharmaceuticals, medical devices and other products or uses of those products that are not approved in other countries or regions.

Do you wish to continue and enter this website?

Yes No