For more information, contact Abbott.
For more information, contact Abbott.
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Vysis LSI TCF3/ PBX1 Dual Color, Dual Fusion Translocation Probe hybridizes to chromosome 19p13.3 (TCF3 - Spectrum Green) and chromosome 1q23 (PBX1 - Spectrum Orange). The PBX1 probe is 635 kb in size and covers the entire PBX1 gene on chromosome 1q23. The TCF3 probe is 730 kb in size and the green probe extends beyond the TCF3 gene to cover a larger region on chromosome 19p13.3.
The signals may also appear diffuse or split depending upon the condensation of the DNA and the relative distances between chromatids. The hybridized probe fluoresces with moderate to bright intensity both in interphase nuclei and on metaphase chromosomes. In interphase nuclei of normal cells, the probe generally appears as two distinct orange signals and two distinct green signals.
Normal Hybridization: Normal hybridization showing two orange and two green signals.
Abnormal Hybridization: Example abnormal hybridization showing two orange, one green and one fusion signals.
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Please be aware that the website you have requested is intended for the residents of a particular country or countries, as noted on that site. As a result, the site may contain information on pharmaceuticals, medical devices and other products or uses of those products that are not approved in other countries or regions.