LUNG CANCER

Vysis PIK3CA SpectrumGreen Probe Kit

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The Vysis PIK3CA SpectrumGreen FISH Probe Kit is designed to detect copy number of 3q26.32 via fluorescence in situ hybridization (FISH) in formalin- fixed, paraffin-embedded (FFPE) lung cancer tissue. The PIK3CA gene locus has been shown to be frequently amplified in many cancers, including lung, ovarian, cervical, gastric, colorectal, breast, head and neck.

 

Normal diploid nuclei are expected to exhibit two green fluorescent PIK3CA signals. A chromosome set that has an extra copy (copies) of PIK3CA will exhibit more than two green fluorescent signals.