Vysis LSI TP53 / CEP 17 FISH Probe Kit

For more information, contact Abbott.

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The Vysis TP53/CEP 17 FISH Probe Kit is intended to detect the copy number of the LSI TP53 probe target located at chromosome 17p13.1 and of the CEP 17 probe target located at the centromere of chromosome 17.

The approximately 172 kb SpectrumOrange TP53 probe contains the complete TP53 gene and is located at chromosome 17p13.1 (chr17:7435119-7606823 March 2006 UCSC Browser). The SpectrumGreen CEP 17 probe is a control probe which hybridizes to the centromere region of chromosome 17p11.1-q11.1.

Normal Hybridization: Nucleus showing the two green and two orange signals.

Abnormal Hybridization: Nucleus showing the two green and one orange signal.