TELOMERIC REGIONS: REARRANGEMENTS, DELETIONS, AND ADDITIONS

Vysis TelVysion Probes

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Telomeres are DNA-protein complexes that cap the ends of eukaryotic chromosomes. Every telomere contains 3 to 20 kb of tandem TTAGGG repeats. The telomere associated repeats (TAR), also known as the subtelomeric repeats, are immediately proximal to the TTAGGG repeats. They contain regions of shared homology between subsets of certain chromosomes.