Vysis BRAF SpectrumGold Probe

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PRODUCT NAME UNIT SIZE ORDER NUMBER GTIN


The SpectrumGold Vysis LSI BRAF fluorescence in situ hybridization (FISH) probe is targeted to the 7q34 region on chromosome 7. The probe is ~510 kb in size and spans the entire BRAF gene. The hybridized probe fluoresces with moderate to bright intensity both in interphase nuclei and on metaphase chromosomes.

Normal Hybridization: Normal diploid nuclei or metaphase chromosome sets are expected to exhibit two gold fluorescent BRAF signals, which correspond to two target loci on chromosome homologues to which the BRAF fluorescent probe is bound: 7q34. A chromosome set that has an extra copy (copies) of BRAF (7q34) will exhibit more than two gold fluorescent signals.