Vysis LSI EWSR1 (22q12) Dual Color Break Apart Rearrangement Probe

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Vysis LSI EWSR1 (22q12) Dual Color Break Apart Rearrangement Probe hybridizes to the band 22q12 (SpectrumGreen on the 3’ (telomeric) side and SpectrumOrange on the 5’ (centromeric) side of the EWSR1 gene breakpoints). The hybridized probe fluoresces with moderate to bright intensity both in interphase nuclei and on metaphase chromosomes.

Normal Hybridization: Result of the hybridization of the LSI EWSR1 Dual Color Break Apart Probe showing two fusion signals.

Abnormal Hybridization: A cell hybridized with the LSI EWSR1 Dual Color Break Apart Probe. The cell in this image shows the one fusion, one orange, and one green signal pattern.