Vysis LSI IGH/FGFR3 Dual Color Dual Fusion Probes
For more information, contact Abbott.
For more information, contact Abbott.
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Vysis LSI IGH/FGFR3 Dual Color Dual Fusion Probes hybridize to chromosome 14q32 (IGH SpectrumGreen) and chromosome 4p16 (FGFR3 SpectrumOrange). The hybridized probe fluoresces with moderate to bright intensity both in interphase nuclei and on metaphase chromosomes.
In a normal cell that lacks the t(4;14), a two orange and two green signal pattern will be observed reflecting the two intact copies of the FGFR3 and IGH regions respectively. In an abnormal cell containing the t(4;14), one orange (FGFR3), one green (IGH), and two fusion signalpattern (der (4) and der (14)) may be observed. Some samples containing the t(4;14) may display signal patterns differently than one orange, one green, and two fusions.
Normal Hybridization: An interphase cell hybridized with the LSI IGH/FGFR3 Dual Color Dual Fusion Probe. The cell shows the two orange (FGFR3),two green (IGH) signal pattern.
Abnormal Hybridization: An interphase cell hybridized with the LSI IGH/FGFR3 Dual Color, Dual Fusion Probe. The cell in this image shows the one orange(FGFR3), one green (IGH), two fusion (der (4) and der (14)) signal pattern.
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Please be aware that the website you have requested is intended for the residents of a particular country or countries, as noted on that site. As a result, the site may contain information on pharmaceuticals, medical devices and other products or uses of those products that are not approved in other countries or regions.