Vysis LSI IGH/FGFR3 Dual Color Dual Fusion Probes

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Product Description
Results of Hybridization
Product Description
Vysis LSI IGH/FGFR3 Dual Color Dual Fusion Probes hybridize to chromosome 14q32 (IGH SpectrumGreen) and chromosome 4p16 (FGFR3 SpectrumOrange). The hybridized probe fluoresces with moderate to bright intensity both in interphase nuclei and on metaphase chromosomes.
Results of Hybridization
In a normal cell that lacks the t(4;14), a two orange and two green signal pattern will be observed reflecting the two intact copies of the FGFR3 and IGH regions respectively. In an abnormal cell containing the t(4;14), one orange (FGFR3), one green (IGH), and two fusion signalpattern (der (4) and der (14)) may be observed. Some samples containing the t(4;14) may display signal patterns differently than one orange, one green, and two fusions.
Normal Hybridization: An interphase cell hybridized with the LSI IGH/FGFR3 Dual Color Dual Fusion Probe. The cell shows the two orange (FGFR3),two green (IGH) signal pattern.
Abnormal Hybridization: An interphase cell hybridized with the LSI IGH/FGFR3 Dual Color, Dual Fusion Probe. The cell in this image shows the one orange(FGFR3), one green (IGH), two fusion (der (4) and der (14)) signal pattern.

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