Vysis LSI MALT1 Dual Color Break Apart Rearrangement Probe

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Product Description
Product Description
Vysis LSI MALT1 Dual Color Break Apart Rearrangement Probe hybridizes to the band 18q21(SpectrumGreen on the 3’ (telomeric) side and SpectrumOrange on the 5’ (centromeric) side of the MALT1 locus breakpoints). The hybridized probe fluoresces with moderate to bright intensity both in interphase nuclei and on metaphase chromosomes.
In a normal cell that lacks a t(18q21) in the MALT1 gene region, a two fusion signal pattern will be observed reflecting the two intact copies of MALT1.

In an abnormal cell with a t(18q21), a one fusion, one green, one orange signal pattern will be observed.
Normal Hybridization: Result of the hybridization of the Vysis LSI MALT1 Dual Color Break Apart Rearrangement Probe as observed in three normal interphase cells.
Abnormal Hybridization: An abnormal cell hybridized with the Vysis LSI MALT1 Dual Color Break Apart Rearrangement Probe. The cell in this image shows the one fusion, one orange, and one green signal pattern indicative of a rearrangement of one copy of the MALT1 gene region.

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