Vysis LSI MYC Dual Color Break Apart Rearrangement Probe

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Vysis LSI MYC Dual Color Break Apart Rearrangement Probe hybridizes to the band region 8q24. The hybridized probe fluoresces with moderate to bright intensity both in interphase nuclei and on metaphase chromosomes.

 

An abnormal nucleus hybridized with the LSI MYC Dual Color Break Apart Rearrangement Probe produces a two orange/green (yellow) fusion (2F) pattern. A one orange, one green, and one fusion pattern (1O1G1F) is expected from a sample with a t(2;8), t(8;22) or t(8;14) having a breakpoint within the gap between the hybridization targets of the LSI MYC probes.

Abnormal Hybridization: LSI MYC Dual Color Break Apart Rearrangement Probe hybridized to an abnormal nucleus showing a one orange, one green and one orange/green fusion (1O1G1F) signal pattern.